Perioperative anesthetic management in a patient at high risk of bleeding secondary to Glanzmann thrombasthenia: a case report
Thiago Medeiros Pereira, Fabrício Tavares Mendonça, Iuri Ferreira Lopes, Sérgio Honorato de Matos
Abstract
Patients with rare inherited bleeding disorders require highly specialized perioperative management, particularly during major surgical procedures. This case report aimed to describe the anesthetic and hemostatic management of a patient with Glanzmann thrombasthenia undergoing partial colectomy under general anesthesia. A descriptive case report was conducted after approval by the local ethics committees and written informed consent from the patient. Perioperative management required multidisciplinary coordination involving anesthesiology, surgery, and hematology teams. The patient received preemptive recombinant activated factor VII (rFVIIa), platelet concentrate, and tranexamic acid. Despite conversion from laparoscopic to open surgery due to intraoperative complications, bleeding was successfully controlled, with maintenance of hemodynamic stability and favorable postoperative evolution until hospital discharge. This case highlights the importance of individualized hemostatic protocols and multidisciplinary planning to ensure safe perioperative management in patients with Glanzmann thrombasthenia.
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References
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