Chronic upper limb pain caused by iatrogenic traumatic neuroma following intramuscular benzathine penicillin injection
Amélie Gabrielle Vieira Falconi, Laura Dornelas Corrêa, Éric Guimarães Machado, Carlos Alberto Menezes Mariosa, Bruno Vítor Martins Santiago
Abstract
This case highlights traumatic neuroma as a rare but potentially disabling late complication of intramuscular injections. Chronic localized neuropathic pain that worsens at night, associated with focal hypersensitivity and positive Tinel-like sign, should prompt evaluation for peripheral nerve injury. Early use of high-resolution ultrasound may enable accurate diagnosis and curative surgical management, preventing years of unnecessary suffering.
References
Oliveira KM, Pindur L, Han Z, Bhavsar MB, Barker JH, Leppik L. Time course of traumatic neuroma development. PLoS One. 2018;13(7):e0200548. https://doi.org/10.1371/journal.pone.0200548. PMid:30011306.
Zhang X, Xu Y, Zhou J, Pu S, Lv Y, Chen Y, et al. Ultrasound-guided alcohol neurolysis and radiofrequency ablation of painful stump neuroma: effective treatments for post-amputation pain. J Pain Res. 2017;10:295-302. https://doi.org/10.2147/JPR.S127157. PMid:28223839.
Submitted date:
01/27/2026
Accepted date:
02/20/2026
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